How far is it from Wheeling, MO, to Syracuse, MO, ?

The driving distance from Wheeling, MO, to Syracuse, MO, is 119 mi by road.

How long does it take to drive from Wheeling, MO, to Syracuse, MO, ?

The drive from Wheeling, MO, to Syracuse, MO, takes approximately 2 h 35 min by car.

What is the best route from Wheeling, MO, to Syracuse, MO, ?

The fastest route from Wheeling, MO, to Syracuse, MO, covers 119 mi with a driving time of approximately 2 h 35 min.

US Route Planner

Wheeling, MOSyracuse, MO

Distance: 119 mi·Duration: 2 h 35 min

Driving from Wheeling, MO to Syracuse, MO takes about 2 h 35 min via US 65. The distance is 119 mi. EV charging is available along the route, including in Emma, MO, Sedalia, MO.

Driving directions

12 · 119 mi

1Depart right onto Grant Street1 mi
2Turn right onto Chicago-Kansas City Expressway9 mi
3Take exit slightly right1 mi
4Turn left88 mi
5Turn slightly left onto MO 7651 mi
6Continue straight1 mi
7Turn straight onto North Ohio Avenue1 mi
8Turn left onto East Pettis Street1 mi

9Continue straight onto West Saline Street1 mi
10Turn right onto North Engineer Avenue1 mi
11Turn left onto East Broadway Boulevard19 mi
12Arrive onto East Front Street

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Popular destinations close by

Syracuse, MO → Tipton, MO6 mi · 10 min Syracuse, MO → Otterville, MO9 mi · 20 min Syracuse, MO → Smithton, MO13 mi · 20 min Syracuse, MO → Clarksburg, MO14 mi · 20 min

Last updated May 14, 2026

Wheeling, MO–Syracuse, MO

Driving directions

Wheeling, MOSyracuse, MO