Fredericktown, MO

united states

Fredericktown, the Madison County seat, sits 90 miles south of St. Louis along Highway 67, which provides the main route to the city through rolling Ozark hills. Highway 72 runs east-west through town toward Cape Girardeau and Ironton, while Route 208 connects north to the mining district. Most visitors arrive via Highway 67 from Farmington or St. Louis, making it a popular stop for those exploring the Mark Twain National Forest. The 1912 Madison County Courthouse anchors the town square with its distinctive red brick and white limestone architecture.